Hyaluronic acid is a polysaccharide found in the extracellular matrix of our tissues, mainly in joints (synovial fluid), the eye (vitreous humor), and the skin, which contains over 50% of the body’s total amount. Its strong hydrophilic properties (promoting tissue hydration and cohesion) and viscoelastic characteristics justify its use in various medical fields (rheumatology, ophthalmology, urology) and in aesthetic medicine for wrinkle filling since the late 1990s.
Benefits of Hyaluronic Acid :
- Biocompatible : No species or tissue specificity, eliminating the need for pre-tests.
- Fully bioresorbable : Minimizing the risk of significant and irreversible side effects.
- Immediate effect : Thanks to its strong hydrophilic properties.
Hyaluronic acid can be synthesized via bacterial fermentation. Laboratories often optimize its structure by cross-linking hyaluronic acid chains to enhance the volumizing effect and reduce rapid degradation by hyaluronidase. As a result, an extensive range of hyaluronic acids is now available, offering a very natural correction that lasts from 9 to 18 months, depending on the product used.
For example, in the Allergan range: Juvederm Ultra 2 and Juvederm Volite are less volumizing products injected superficially to densify the dermis and treat fine lines, while Juvederm 3, 4, and Juvederm Voluma are denser products injected deeply to restore volume to the cheeks and chin area.